Biochemistry Demystified By Sharon Walker David McMahon

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Biochemistry Demystified Download Pdf

Introduction: Biochemistry

You, biochemist(Biochemistry) to be, have happened upon this field at a remarkable time. Human healthcare is undergoing revolutionary changes based on new abilities to understand and to manipulate the human system at a molecular level. You have a chance not only to understand this remarkable machine but also to remove defects and improve life. But first, you need to know biochemistry.
You will need to have a background in the discipline of chemistry to understand biochemistry because biomolecules are controlled by the same forces that define other chemical processes. In this chapter, we will undergo a broad review of basic tenets of chemistry. You need to understand:
• Forces that hold atoms and molecules together
• Forces that drive reactions
To understand this review, you need to know that positively-charged particles called protons exist in the nucleus of an atom, together with neutral particles called neutrons. Negatively charged electrons exist in orbitals surrounding the nucleus. Atoms have the same number of electrons as protons, so the atom is neutrally charged. Simple enough? For the purposes of this discussion, you can envision the negatively charged electrons as existing in defined orbitals, or shells, around the nucleus. This is the familiar model of the atom, called the Bohr atom (after Dr. Bohr, of course). The electrons surrounding the nucleus exist in a specific region of space resembling clouds at specific distances from the nucleus. For the discussion of the electron orbitals, envision a series of shells that must be filled in a certain order. Note that it is actually more correct to consider the electrons as existing in a cloud around the nucleus. Some positions in the cloud are more probable than others, resulting in the simplistic picture of layers

Contents

CHAPTER 1 The Chemistry of Biomolecules
CHAPTER 2 Cell Structures and Cell Division
CHAPTER 3 Carbohydrates
CHAPTER 4 Lipids
CHAPTER 5 Lipid Metabolism
CHAPTER 6 Protein Structure
CHAPTER 7 Protein Assembly and Disassembly
CHAPTER 8 Nucleic Acids and Nucleotides
CHAPTER 9 Enzymes
CHAPTER 10 Glycolysis
CHAPTER 11 The Citric Acid Cycle and Oxidative Phosphorylation
CHAPTER 12 Control of Chemical Processes—Signal Biomolecules
CHAPTER 13 Specialty Functions
CHAPTER 14 Bio information, Analytical Techniques, and Bioinformatics
APPENDIX
Index

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