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Introduction: Vaccine Development
Getting Started with Vaccine Development, RESEARCH OBJECTIVES NLP-VACCINE-MRSA National Laboratory Pathfinder – Vaccine – Methicillin-resistant Staphylococcus aureus (NLP-Vaccine-MRSA) investigation uses microgravity to examine, Methicillin-resistant Staphylococcus aureus, a pathogenic (disease-causing) organism resistant to most common antibiotics, to develop a potential vaccine for the
prevention of infection on Earth and in microgravity.NLP-VACCINE-SURVEY
National Laboratory Pathfinder – Vaccine – Survey (NLP-Vaccine-Survey) investigation uses
microgravity to examine several pathogenic (disease-causing) microorganisms to assist in the
development of potential vaccines for the prevention of infections on Earth and in microgravity.
There is currently no vaccine available for the strains of organisms being examined by the NLPVaccine
series of investigations. This research may help Vaccine Development against these life-threatening
Recombinant attenuated Salmonella vaccine (RASV) evaluates the ability of the spaceflight platform to accelerate recombinant attenuated Salmonella vaccine development against pneumococcal pneumonia, which causes life-threatening diseases (pneumonia, meningitis, bacteremia) that kill over 10 million people annually, particularly children and elderly who are less responsive to current anti-pneumococcal vaccines.
The overall goal of the RASV the experiment is to use spaceflight as an innovative platform to facilitate the design and development of next-generation vaccines with improved efficacy and protective immune
responses while minimizing unwanted side effects by 1) providing novel gene targets for
vaccine improvement and development, and 2) re-formulating existing vaccines.
Biology and Biotechnology
Earth and Space Science
Earth Remote Sensing
Educational Activities and Outreach
Technology Development and Demonstration
Results from ISS Operations and Other Projects
Technology Development and Demonstration: Spacecraft and Orbital Environments